The Dose Finding and Other Topics in Drug Development conference will be held June 8-9, 2023, at the Storrs campus of The University of Connecticut in honor of Dr. Naitee Ting’s 70th birthday.
Finding the right dose(s) is one of the most important objectives in new drug development. In Phase I clinical development, one of the objectives is to escalate test doses from low to high. The low doses should be safe, then escalate up to the maximally tolerable dose (MTD). Phase Ⅱ clinical trials then lower test doses to the minimal efficacious dose (MinED). Dose range of a study drug can be thought of as the doses between MinED and MTD. From this dose range, one or a few doses are selected for Phase Ⅲ confirmation. In practice, dose finding is a very difficult challenge in every phase of clinical development for new drugs.
The first book on the subject, Dose Finding in Drug Development, was published in 2006 and edited by Naitee Ting. This book is highly regarded by his peers and is considered a leading reference title in the environs of dose response for clinical trials. Building upon basic principles found in the book, many advancements have occurred since. The conference covers these important topics, as well as other related topics, and celebrates the 70th birthday of Naitee Ting who helped to pioneer this field of research.
The conference brings together stakeholders from various scientific disciplines who seek to share research in a collegial environment for the advancement of dose-finding science in clinical trials. The conference also provides a collaborative environment for young researchers seeking to learn more about the field, develop networks, and connect with top researchers. Modalities include oral presentations, short courses, poster exhibits, and flash talks. Located between Boston and New York City, the University of Connecticut at Storrs is a major research and teaching institution located in a picturesque environment.
It is a distinct honor to recognize Dr. Naitee Ting’s many contributions to statistics and the pharmaceutical sciences at the Dose Finding and Other Topics in Drug Development conference.